This course is an introduction to solid state characterization of organic molecules. Techniques include x-ray powder diffraction (XRPD), thermal methods spectroscopic methods, and water uptake.

For each technique, basic theory is presented along with its application to organic molecules. Information on instrumentation, sample preparation, and data analysis is included in the modules. Use of the technique to differentiate and quantitate solid forms (polymorphs) is discussed and case studies are presented to show how the measurements were used in real life situations.

• XRPD theory and best practices
• Thermal analysis methods and how they are used together
• Spectrometric methods overview and when to use them
• Water sorption measurements and how to determine when water may be an issue
• Case studies to show how the techniques were used to solve real world problems

Anyone who works with organic molecules, such as synthesis, crystallization, characterization, analysis, use, formulation, physical and chemical stability.

Organic chemists, process chemists, materials scientists, analytical chemists, pharmaceutical scientists, formulation scientists, patent attorneys.

Managers and supervisors who need a basic understanding of solid form characterization and how it will affect their ultimate goals will also find this course useful.